当研究室では有機化学を研究基盤として、周期表を縦断・横断する元素化学を展開し、化学物質の反応、性質、構造について研究します。実験的手法のみならず理論計算的手法も利用して、新しい分子を能動的かつ精密にデザインし、新たな分子変換反応の開発、新合成法の開拓、未知機能の創出に挑みます。元素の様々な組み合わせで構成される分子の反応性・機能性が、元素のどのような性質に由来するのかを分子構造・電子構造を理解することによって明らかにし、既存の学問領域にとらわれない新しい学理を探求することを目指します。

研究テーマ

• 有機化学、無機化学、金属化学の枠を超えた周期表横断型化学
• 物質科学・生命科学を支援する高度分子変換法の開発
• 計算化学を活用した機能性物質の創成

主要論文

1. Komagawa, S., Usui, S., Haywood, J., Harford, P. J., Wheatley, A. E. H., Matsumoto, Y., Hirano, K., Takita, R., and Uchiyama M.:
   "Amidocuprates for Directed ortho Cupration (DoC): Structural Study, Mechanistic Investigation, and Chemical Requirements"
   Angew. Chem. Int. Ed., 51, 12081-12085 (2012).
2. Muranaka, A., Ohira, S., Hashizume, D., Koshino, H., Kyotani, F., Hirayama, M., and Uchiyama, M.:
   "[18]/[20]pi Hemiporphyrazine: A Redox Switchable Near- infrared Dye"
   J. Am. Chem. Soc., 134, 190-193 (2012).
3. Wang, C., Ozaki, T., Takita, R., and Uchiyama, M.:
   "Aryl Ether as Negishi Coupling Partner: An Approach for Constructing C-C Bond under Mild Conditions"
   Chem. Eur. J., 18, 3482-3485 (2012).
4. Matsushita, O., Derkacheva,V. M., Muranaka, A., Shimizu, S., Uchiyama, M., Lukyanets, E. A. and Kobayashi, N.:
   "Rectangular-Shaped Expanded Phthalocyanines with Two Central Metal Atoms"
   J. Am. Chem. Soc., 133, 3411-3418 (2012).
5. Watanabe, S., Fukuchi, Y., Fukasawa, M., Sassa, T., Uchiyama, M., Yamashita, T., Matsumoto, M., and Aoyama, T.:
   "Electron Donor and Acceptor Spatial Distribution in Structured Bulk Heterojunction Photovoltaic Devices Induced by Periodic Photopolymerization"
   Langmuir, 28, 10305-10309 (2012).
6. Maeda, S., Komagawa, S., Uchiyama, M., and Morokuma, K.:
   "Finding Reaction Pathways for Multicomponent Reactions: The Passerini Reaction Is a Four-Component Reaction "
   Angew. Chem. Int. Ed., 50, 644-649 (2011).
7. Muranaka, A., Yonehara, M., and Uchiyama, M.:
   "Azulenocyanine: A New Family of Phthalocyanines with Intense Near-IR Absorption."
   J. Am. Chem. Soc., 132, 7844-7845 (2010).
8. Sada, M., Komagawa, S., Uchiyama, M., Kobata, M., Mizuno, T., Utimoto, K., Oshima, K., and Matsubara, S.:
   "Reaction Pathway of Methylenation of Carbonyl Compounds with Bis(iodozincio)methane"
   J. Am. Chem. Soc., 132, 17452-17458 (2010).
9. Naka, H., Morey, J. V., Haywood, J., Eisler, D. J., McPartlin, M., Garcia, F., Kudo, H., Kondo, Y., Uchiyama, M., and Wheatley, A. E. H.:
   "A Mixed Alkyl-amido Aluminate as a Kinetically Controlled Base."
   J. Am. Chem. Soc., 130, 16193-16200 (2008).
10. Uchiyama, M., Kobayashi, Y., Furuyama, T., Nakamura, S., Kajihara, Y., Miyoshi, T., Sakamoto, T., Kondo, Y., and Morokuma, K.:
    "Generation and Suppression of 3-/4-Functionalized Benzynes Using Zinc Ate Base (TMP-Zn-ate): New Approaches to Multi-substituted Benzenes."
    J. Am. Chem. Soc., 130, 472-480 (2008).