主要論文

1. Hibino, K., Shibata, T., Yanagida, T., and Sako, Y.:
   "Single-molecule kinetic analysis of RAF activation in the ternary complex among RAF, RasGTP, and the kinases on the plasma membrane of living cells"
   J. Biol. Chem. 286, 36460-36468 (2011)
2. Sako, Y, Hiroshima, M, Pack, C-G, Okamoto, K, Hibino, K, Yamamoto, A.:
   "Live-cell single-molecule detection in systems biology"
   WIREs Systems Biology and Medicine, doi:10.1002/wsbm.161 (2011).
3. Hibino, K., Shibata, T., Yanagida, T., and Sako, Y.:
   "A RasGTP-induced conformational change in C-RAF is essential for accurate molecular recognition."
   Biophys. J. 97, 1277-1287 (2009)
4. Morimatsu, M., Takagi, H., Ota, K. G., Iwamoto, R., Yanagida, T., Sako, Y.:
   "Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed using single-molecule analysis"
   Proc. Natl. Acad. Sci. USA, 104, 18013-18018 (2007)
5. Teramura, Y., Ichinose, J., Takagi, H., Nishida, K., Yanagida, T., Sako, Y.:
   "Single-molecule analysis of epidermal growth factor binding on the surface of living cells"
   EMBO J., 25, 4215-4222 (2006)
6. Sako, Y.:
   "Imaging single molecules for systems biology"
   Mol. Syst. Biol. doi:10.1038/msb4100100 (2006)
7. Uyemura, T., Takagi, H., Yanagida, T., Sako, Y.:
   "Single-molecule analysis of epidermal growth factor signaling that leads to ultrasensitive calcium response"
   Biophys. J., 88, 3720-3730 (2005)
8. Sako, Y., Yanagida, T.:
   "Single-molecule visualization in cell biology"
   Nature Rev. Mol. Cell Biol., 4, SS1-5 (2003)
9. Sako, Y., Minoguchi, S., Yanagida, T.:
   "Single molecule imaging of EGFR signal trasnduction on the living cell surface"
   Nature Cell Biol., 2, 168-172 (2000)

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