主要論文

1. Israelson A, Arbel N, Da Cruz S, Ilieva H, Yamanaka K, Shoshan-Barmatz V, Clevalend DW.:
   " Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse 　Model of Inherited ALS."
   Neuron, 67: 575-87, (2010).
2. Lobsiger CS, Boillee S, McAlonis-Downes M, Khan AM, Feltri ML, Yamanaka K, Cleveland DW.:
   " Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice."
   Proc. Natl. Acad. Sci., USA, 106: 4465-70, (2009).
3. Yamanaka K, Boillee S, Roberts EA, Garcia ML, McAlonis-Downes M, Mikse OR, Cleveland DW, Goldstein LSB.:
   " Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice."
   Proc. Natl. Acad. Sci., USA, 105: 7594-7599, (2008).
4. Yamanaka, K., Chun SJ., Boillee, S., Fujimori-Tonou, N., Yamashita, H., Gutmann DH., Takahashi, R., Misawa, H., Cleveland, DW.:
   " Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis."
   Nat. Neurosci., 11, 251-253 (2008).
5. Yamashita H, Kawamata J, Okawa K, Kanki R, Nakamizo T, Hatayama T, Yamanaka K, Takahashi R, Shimohama S.:
   " Heat-shock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase; clues to a possible strategy for treating ALS."
   J. Neurochem., 102, 1497-1505 (2007)
6. Boillee, S., Yamanaka, K., Lobsiger, CS., Copeland, NG., Jenkins, NA., Kassiotis, G., Kollias, G., Cleveland, DW.:
   " Onset and Progression in Inherited ALS determined by Motor Neurons and Microglia"
   Science, 312, 1389-1392 (2006).
7. Yamanaka, K., Miller, TM., McAlonis-Downes, M., Chun, SJ., Cleveland, DW.:
   " Progressive axonal degeneration and slowness in ALS2-deficient mice"
   Ann. Neurol., 60, 95-104 (2006).
8. Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK.:
   " Gene transfer demonstrates that muscle is not a primary target for non-cell autonomous toxicity in familial amyotrophic lateral sclerosis."
   Proc. Natl. Acad. Sci. USA, 103, 19546-19551 (2006).
9. Smith, RA., Miller, TM., Yamanaka, K., Monia, BP., Condon, TP., Hung, G., Lobsiger, CS., Ward, CM., McAlonis-Downes, M., Wei, H., Wancewicz, EV., Bennett, CF., Cleveland, DW.:
   " Antisense Oligonucleotides as a Therapy for Neurodegenerative diseases"
   J. Clin. Invest., 116, 2290-2296 (2006).

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