主要論文

1. Suzuki, G., Shimazu, N., and Tanaka, M.:
   "A Yeast Prion, Mod 5, Promotes Acquired Drug Resistance for Cell Survival under Environmental Stress"
   Science, in press (2012)
2. Tanaka, M.:
   " Protein misfolding: tracking a toxic polyglutamine epitope"
   Nat. Chem. Biol., 7, 861-862 (2011).
3. Tonoki A, Kuranaga E, Ito N, Nekooki-Machida Y, Tanaka M, and Miura M:
   " Aging causes distinct characteristics of polyglutamine amyloids in vivo"
   Genes Cells, 16, 557-64 (2011).
4. Foo CK, Ohhashi Y, Kelly MJ, Tanaka M, and Weissman JS:
   " Radically different amyloid conformations dictate the seeding specificity of a chimeric Sup35 prion"
   J. Mol. Biol., 408, 1-8 (2011)
5. Ohhashi, Y., Ito, K., Toyama, GH, Weissman, JS., and Tanaka, M.:
   " Differences in prion strain conformations result from non-native interactions in a nucles"
   Nat. Chem. Biol., 6, 225-230 (2010).
6. Nekooki-Machida, Y., Kurosawa, M., Nukina, N., Ito, K, Oda, T., and Tanaka, M.:
   " Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity"
   Proc. Natl. Acad. Sci. U. S. A., 106, 9679-9684 (2009).
7. Krzewska, J., Tanaka, M., Burston, SG., and Melki, R.:
   " Biochemical and functional analysis of the assembly of full-length Sup35p and its prion-forming domain"
   J. Biol. Chem., 282, 1679-1686 (2007).
8. Tanaka, M., Collins, SR., Toyama, BH., and Weissman, JS.:
   " The physical basis of how prion conformations determine strain phenotypes"
   Nature, 442, 585-589 (2006).
9. Tanaka, M., Chien, P., Yonekura, K., and Weissman, JS.:
   " Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins"
   Cell, 121, 49-62 (2005).
10. Tanaka, M., Machida, Y., Niu, S., Ikeda, T., Jana, NR., Doi, H., Kurosawa, M., Nekooki, M., and Nukina, N.:
    " Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease"
    Nat. Med., 10, 148-154 (2004).

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