主要論文

1. Takashima, T., Yokoyama, C., Mizuma, H., Yamanaka, H., Wada, Y., Onoe, K., Nagata, H., Tazawa, S., Doi, H., Takahashi, K., Morita, M., Kanai, M., Shibasaki, M., Kusuhara, H., Sugiyama, Y., Onoe, H., and Watanabe, Y.:
   "Developmental changes in P-glycoprotein function in the blood-brain barrier of non-human primates: PET study with R-[11C] verapamil and [11C] oseltamivir."
   J. Nucl. Med., in press, 2011.
2. Takahashi, K., Yamagishi, G., Hiramatsu, T., Hosoya, A., Onoe, K., Doi, H., Nagata, H., Wada, Y., Onoe, H., Watanabe, Y., and Hosoya, T.:
   "Practical synthesis of precursor of [N-methyl-(11)C]vorozole, an efficient PET tracer targeting aromatase in the brain."
   Bioorg. Med. Chem., 19(4): 1464-1470, 2011.
3. Yamashita, S., Takashima, T., Kataoka, M., Oh, H., Sakuma, S., Takahashi, M., Suzuki, N., Hayashinaka, E., Wada, Y., Cui, Y., and Watanabe, Y.:
   "PET imaging of the gastrointestinal absorption of orally administered drugs in conscious and anesthetized rats."
   J. Nucl. Med., 52(2): 249-56, 2011.
4. Kuboyama, T., Nakamura, M., Yoshino, M., Cui, Y.L., Sako, T., Wada, Y., Imanishi, T., Obika, S., Watanabe, Y., Suzuki, M., and Doi, H.:
   "Stoichiometry-focused 18F-labeling of alkyne-substituted oligodeoxynucleotides using azido([18f]fluoromethyl)benzenes by Cu-catalyzed Huisgen reation."
   Bioorg. Med. Chem., 19(1): 249-255, 2011
5. Takashima, T., Nagata, H., Nakae, T., Cui, Y., Wada, Y., Kitamura, S., Doi, H., Suzuki, M., Maeda, K., Kusuhara, H., Sugiyama, Y., and Watanabe, Y.:
   "PET studies using 15R-[11C]TIC-Me for the evaluation of hepatobiliary transport."
   J. Pharmacol. Exp. Ther., 335(2): 314-323, 2010.
6. Tanaka, K., Minami, K., Tahara, T., Fujii, Y., Siwu, E.R., Nozaki, S., Onoe, H., Yokoi, S., Koyama, K., Watanabe, Y., and Fukase, K.:
   "Electrocyclization-based labeling allows efficient in vivo imaging of cellular trafficking."
   Chem. Med. Chem., 5(6): 841-845, 2010.
7. Takashima-Hirano, M., Shukuri, M., Takashima, T., Goto, M., Wada, Y., Watanabe, Y., Onoe, H., Doi, H., and Suzuki, M.:
   "General Method for the (11)C-Labeling of 2-Arylpropionic Acids and Their Esters: Construction of a PET Tracer Library for a Study of Biological Events Involved in COXs Expression. "
   Chemistry, 16(14):4250-4258, 2010.
8. Akazawa, K.H., Cui, Y.L., Tanaka, M., Kataoka, Y., Yoneda, Y., and Watanabe, Y.:
   "Mapping of regional brain activation in response to fatigue-load and recovery in rats with c-Fos immunohistochemistry. "
   Neurosci. Res., 66(4): 372-379, 2010.
9. Cui, Y.L., Takashima, T., Takashima-Hirano, M., Wada, Y., Shukuri, M., Tamura, Y., Onoe, H., Kataoka, Y., and Watanabe, Y.:
   "11C-PK11195 PET for the in vivo evaluation of neuroinflammation in the rat brain after cortical spreading depression."
   J. Nucl. Med., 50(11):1904-1911, 2009.
10. Yamato, M., Kataoka, Y., Mizuma, H., Wada, Y., and Watanabe, Y.:
    "PET and macro- and microautoradiographic studies combined with immunohistochemistry for monitoring rat intestinal ulceration and healing processes."
    J. Nucl. Med., 50(2):266-273, 2009.

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