List of Selected Publications

1. Hashimoto-Tane A., Yokosuka T., Sakata-Sogawa K., Sakuma M., Ishihara C., Tokunaga M., Saito T.:
   "Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation."
   Immunity. 34:919-931, 2011.
2. Yokosuka, T., Kobayashi, W., Takamatsu, M., Sakata-Sogawa, K., Zeng, H., Hashimoto-Tane, A., Yagita, H., Tokunaga, M., Saito, T.:
   "Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation."
   Immunity. 33: 326-339, 2010.
3. Takeuchi A, Itoh Y, Takumi A, Ishihara C, Arase N, Yokosuka T, Koseki H, Yamasaki S, Takai Y, Miyoshi J, Ogasawara K, and Saito T.:
   "CRTAM confers late-stage activation of CD8⁺ T cells to regulate retention within lymph node."
   J. Immunol. 183: 4220-4228, 2009.
4. Yamasaki, S., Matsumoto, M., Takeuchi, O., Matsuzawa, T., Ishikawa, E., Sakuma, M., Tateno, H., Uno, J., Hirabayashi, J., Mikami, Y., Takeda, K., Akira, S., and Saito, T.:
   "C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia."
   Proc. Natl. Acad. Sci. USA. 10: 1897-1902, 2009.
5. Yokosuka, T., Kobayashi, W., Sakata-Sogawa, K., Takamatsu, M., Hashimoto-Tane, A., Dustin, M.L., Tokunaga, M. and Saito, T.:
   "Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters through protein kinase C θ translocation."
   Immunity. 29: 589-601, 2008.
6. Yamasaki, S., Ishikawa, E., Sakuma, M., Hara, H., Ogata, K. and Saito, T.:
   "Mincle is an ITAM-coupled activating receptor that senses damaged cells."
   Nat. Immunol. 9: 1179-1188, 2008.
7. Hara, H., Ishihara, C., Takeuchi, A., Imanishi, T., Xue, L., Morris, S.W., Inui, M., Takai, T., Shibuya, A., Saijo, S., Iwakura, Y., Ohno, N., Koseki, H., Yoshida, H., Penninger, J.M. and Saito, T.:
   "The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors."
   Nat. Immunol. 8: 619-629, 2007.
8. Suzuki, N., Suzuki, S., Millar, D. G., Unno, M., Hara, H., Calzascia, T., Yamasaki, S., Yokosuka, T., Chen, N-J., Elford, A. R., Suzuki, J-I., Takeuchi, A., Mirtsos, C., Bouchard, D., Ohashi, P. S., Yeh, W-C. and Saito, T.:
   "A critical role for the innate immune signaling molecule IRAK-4 in T cell activation."
   Science 311:1927-1932, 2006.
9. Yamasaki, S. Ishikawa, E., Sakuma, M., Ogata, K., Sakata-Sogawa, K., Hiroshima, M., Wiest, D.L., Tokunaga, M. and Saito, T.:
   "Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development."
   Nat Immunol. 7: 67-75, 2006.
10. Yokosuka, T. Sakata-Sogawa, K., Kobayashi, W., Hiroshima, M., Hashimoto-Tane, A., Tokunaga, M., Dustin, M.L. and Saito, T.:
    "Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap 70 and SLP-76."
    Nat Immunol. 6: 1253-1262, 2005.

Members