List of Selected Publications

1. Fukagawa, A., Hiroshima, M., Sakane, I.,and Tokunaga, M.:
   "Stochastic emergence of multiple intermediates detected by single-molecule quasi-static mechanical unfolding of protein."
   PLoS One. 4 (8), e6599 (2009).
2. Miletic, AV., Graham, DB., Sakata-Sogawa, K., Hiroshima, M., Hamann, HJ., Cemerski, S., Kloeppel, T., Billadearu,DD., Kanagawa,O., Tokunaga, M., and Swat, W.:
   "Vav Links the T Cell Antigen Receptor to the Actin Cytoskelton and T Cell Activation Independently of Intrinsic Guanine Nucleotide Exchange Activity."
   BIOPHYSICS, 5, 25-35 (2009)
3. Fukagawa, A., Hiroshima, M., Sakane, I.,and Tokunaga, M.:
   "Observation of Multiple and Stochastic Transition States by a Feedback-controlled Single-molecule Force Measurement."
   Anal Sci., 25, 5-7 (2009).
4. Yokosuka, T, Kobayashi, W., Sakata-Sogawa, K., Takamatsu, M., Hashimoto-Tane, A., Dustin, M.L., Tokunaga, M. and Saito,T.:
   "Spatiotemporal regulation of T cell co-stimulation by TCR-CD28 microclusters through PKCq translocation."
   Immunity, 29, 589-601 (2008)
5. Tokunaga, M., Imamoto, N., Sakata-Sogawa, K.:
   "Highly inclined thin illumination enables clear single-molecule imaging in cells."
   Nat Methods, 5, 159-161 (2008).
6. Yamasaki, S., Sakata-Sogawa, K., Hasegawa, A., Suzuki, T., Kabu, K., Sato, E., Kurosaki, T., Yamashita, S., Tokunaga, M., Nishida, K., Hirano, T.:
   "Zinc is a novel second messenger."
   J. Cell Biol. 177, 637-645 (2007)
7. Yamasaki, S., Ishikawa, E., Sakuma, M., Ogata, K., Sakata-Sogawa, K., Hiroshima, M., Wiest, D. L., Tokunaga, M., and Saito, T.:
   "Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development."
   Nature Immunol., 7, 67-75 (2006).
8. Yokosuka, T., Sakata-Sogawa, K., Kobayashi, W., Hiroshima, M., Hashimoto-Tane, A., Tokunaga, M., Dustin, M. L., and Saito, T.:
   "Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76."
   Nature Immunol., 6, 1253-1262 (2005).
9. Kitamura, K., Tokunaga, M., Iwane, A. H., and Yanagida, T.:
   "A single myosin head moves along an actin filament with regular steps of 5.3 nanometres."
   Nature, 397, 129-134 (1999).
10. Tokunaga, M., Kitamura, K., Saito, K., Iwane, A. H., and Yanagida, T.:
    "Single Molecule Imaging of Fluorophores and Enzymatic Reactions Achieved by Objective-type Total Internal Reflection Fluorescence Microscopy."
    Biochem. Biophys. Res. Comm., 235, 47-53 (1997).

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