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Plant Productivity Systems Research Group
Hitoshi SAKAKIBARA
Group Director
Hitoshi SAKAKIBARA (Ph.D.)
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Research Areas

Plants synthesize a variety of organic compounds through photosynthesis and unique metabolic pathways. Numerous metabolic processes are involved in plant productivity, such as an efficient photosynthetic capacity, effective transport, and the storage of biosynthesized products. We have conducted research and development on production control aimed at effectively utilizing plant resources that aid in the production of useful biomaterials and energy. On the basis of plant hormone research, we are conducting studies to understand systems involved in plant productivity, sink-source regulation, and effective material transport, as well as R&D on techniques aimed at productivity control. We hope to utilize various genomic functions of model plants and comparative studies on genomes as a foundation for the production of more and better crops and trees.

Research Subject

  1. Identification of key genes regulating agronomical traits improving crop productivity
  2. Functional analysis of key genes regulating plant productivity, especially enzymes involved in cytokinin biosynthesis and metabolism
  3. Development of clean-up technology of heavy metal pollutants using bryophyte
  4. Identidfication of key genes in agricultural traits using high-throughput hormone analysis system

Related links

  1. RIKEN Plant Science Center Website_Laboratories PageNew Window

Press release

January 11, 2012
Mechanism of Efficient Nitrate Uptake under Low External Supply in Arabidopsis RevealedNew Window
July 4, 2011
A New Role for Cytokinin Plant HormonesNew Window

RIKEN RESEARCH

June 11, 2010
Time to grow
Fresh insights into the workings of the 'internal timetable' of plants could ultimately guide the engineering of hardier, faster-growing cropsNew Window
June 20, 2008
Sights set on plant tumor trigger
New insight into how a key enzyme causes plant tumors could ultimately reduce crop lossesNew Window
June 22, 2007
'Lonely guy' helps crops to flourish
New insights into the regulation of an important plant hormone could extend the agricultural potential of rice and other cropsNew Window

List of Selected Publications

  1. Kiba, T., Feria-Bourrellier, A.-B., Lafouge, F., Lezhneva, L., Boutet-Mercey, S., Orsel, M., Bréhaut, V., Miller, A., Daniel-Vedele, F., Sakakibara, H. and Krapp, A.:
    " The Arabidopsis nitrate transporter NRT2.4 plays a double role in roots and shoots of nitrogen-starved plants."
    Plant Cell 24: doi:10.1105/tpc.111.092221. (2012)
  2. Tokunaga,H., Kojima, M., Kuroha, T., Ishida, T., Sugimoto, K., Kiba, T. and Sakakibara, H.:
    " Arabidopsis lonely guy (LOG) multiple mutants reveal a central role of the LOG-dependent pathway in cytokinin activation."
    Plant J. 69: 355-365 (2012)
  3. Nakamichi, N., Kiba, T., Henriques, R., Mizuno, T., Chua, N.-H. and Sakakibara, H.:
    " PSEUDO-RESPONSE REGULATORS 9, 7 and 5 are transcriptional repressors in the Arabidopsis circadian clock."
    Plant Cell 22: 594-605 (2010)
  4. Kuroha, T., Tokunaga, H., Kojima, M., Ueda, N., Ishida, T., Nagawa, S., Fukuda, H., Sugimoto-Shirasu, K. and Sakakibara, H.:
    " Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis"
    Plant Cell 21: 3152-3169 (2009)
  5. Kojima, M., Kamada-Nobusada, T., Komatsu, H., Takei, K., Kuroha, T., Mizutani, M., Ashikari, M., Ueguchi-Tanaka, M., Matsuoka, M., Suzuki, K. and Sakakibara, H.:
    " High-throughput and high-sensitive analysis of plant hormones using MS-probe modification and liquid chromatography-tandem mass spectrometry: an application for hormone profiling in Oryza sativa"
    Plant Cell Physiol. 50: 1201-1214 (2009)
  6. Sugawara, H., Ueda, N., Kojima, M., Makita, N., Yamaya, T. and Sakakibara, H.:
    " Structural insight into the reaction mechanism and evolution of cytokinin biosynthesis"
    Proc. Natl. Acad. Sci. U.S.A. 105: 2734-2739 (2008)
  7. Kurakawa, T., Ueda, N., Maekawa, M., Kobayashi, K., Kojima, M., Nagato, Y., Sakakibara, H. and Kyozuka, J.:
    " Direct control of shoot meristem activity by a cytokinin activating enzyme"
    Nature 445: 652-655 (2007)
  8. Sakakibara, H.:
    " Cytokinins: Activity, biosynthesis and translocation"
    Annu. Rev. Plant Biol. 57: 431-449 (2006)
  9. Sakakibara, H., Takei, K., and Hirose, N.:
    " Interactions between nitrogen and cytokinin in the regulation of metabolism and development"
    Trends in Plant Science 11: 440-448 (2006)
  10. Ashikari, M., Sakakibara, H., Lin, S.-Y., Yamamoto, T., Takashi, T., Nishimura, A., Angeles, E. R., Qian, Q., Kitano, H. and Matsuoka, M.:
    " Cytokinin oxidase regulates rice grain production"
    Science, 309: 741-745 (2005)

Members

Principal Investigator

Hitoshi SAKAKIBARA
Group Director

Members

Misao ITOUGA
Senior Research Scientist
Takatoshi KIBA
Research Scientist
Tomoe NOBUSADA
Research Scientist
Mikiko KOJIMA
Technical Scientist
Toru KUDO
Postdoctoral Researcher
Toshihisa NOMURA
Visiting Researcher
Radhika VENKATESAN
Visiting Researcher
Hiroki TOKUNAGA
Junior Research Associate
Nanae MORI
Technical Staff
Nobue MAKITA
Technical Staff
Yukari KATO
Technical Staff