Plant Genomic Network Research Team
Team Leader
Motoaki SEKI (D.Sci.)
It is important to understand plant molecular responses to various environmental stress, such as drought, cold, high-salinity and heat for improvement of plant productivity under the adverse environment. We are analyzing novel transcriptional and post-transcriptional regulation mechanism through chromatin remodeling and RNAs in abiotic stress responses by genomic approaches. We collaborate with other research teams inside and outside the center on whole-genome transcriptome and epigenome analysis using the cutting-edge genome technologies, such as tiling array and next generation sequencers. We are also establishing a cassava functional genomics platform and advancing cassava molecular breeding in collaboration with oversea research organizations (CIAT, Mahidol Univ., AGI etc.).
- Whole-genome transcriptome and epigenome analyses in drought, cold, high-salinity, heat stress and ABA responses using cutting-edge genome technologies
- Functional analysis of genes and functional RNAs involved in environmental stress and ABA responses
- Analysis of (post)transcriptional regulation mechanism through chromatin remodeling and RNAs
- Establishment of cassava functional genomics platform and its application to molecular breeding
- January 27, 2009
- Suppression of mRNA-like non-coding RNAs (nc-RNAs) by the quality control surveillance mechanism for defective mRNAs, elucidated through the first comprehensive analysis for expression regulation of mRNA-like nc-RNAs
- September 09, 2008
- Characterization of chromatin state responding to environmental stress
- July 16, 2008
- Identification of ca. 7,300 new non-coding RNAs of Arabidopsis thaliana
- Seki, M., Narusaka, M., Kamiya, A., Ishida, J., Satou, M., Sakurai, T., Nakajima, M., Enju, A., Akiyama, K., Oono, Y., Muramatsu, M., Hayashizaki, Y., Kawai, J., Carninci, P., Itoh, M., Ishii, Y., Arakawa, T., Shibata, K., Shinagawa, A., Shinozaki, K.:
" Functional annotation of a full-length Arabidopsis cDNA collection"
Science, 296, 141-145 (2002) - Seki, M., Narusaka, M., Ishida, J., Nanjo, T., Fujita, M., Oono, Y., Kamiya, A., Nakajima, M., Enju, A., Sakurai, T., Satou, M., Akiyama, K., Taji, T., Yamaguchi-Shinozaki, K., Carninci, P., Kawai, J., Hayashizaki, Y., Shinozaki, K.:
" Monitoring the expression profiles of 7000 Arabidopsis genes under drought, cold, and high-salinity stresses using a full-length cDNA microarray"
Plant Journal, 31, 279-292 (2002) - Seki, M., Narusaka, M., Abe, H., Kasuga, M., Yamaguchi-Shinozaki, K., Carninci, P., Hayashizaki, Y., Shinozaki, K.:
" Monitoring the expression pattern of 1300 Arabidopsis genes under drought and cold stresses using a full-length cDNA microarray"
Plant Cell, 13, 61-72 (2001) - Yamada, K., Lim, J., Dale, J.M., Chen, H., Shinn, P., Palm, C.J., Southwick, A.M., Wu, H.C., Kim, C., Nguyen, M., Pham, P., Cheuk, R., Karlin-Neumann, G., Liu, S.X., Lam, B., Sakano, H., Wu, T., Yu, G., Miranda, M., Quach, H.L., Tripp, M., Chang, C.H., Lee, J.M., Toriumi, M., Chan, M.M.H., Tang, C.C., Onodera, C.S., Deng, J.M., Akiyama, K., Ansari, Y., Arakawa, T., Banh, J., Banno, F., Bowser, L., Brooks, S., Carninci, P., Chao, Q., Choy, N., Enju, A., Goldsmith, A.D., Gurjal, M., Hansen, N.F., Hayashizaki, Y., Johnson-Hopson, C., Hsuan, V.W., Iida, K., Karnes, M., Khan, S., Koesema, E., Ishida, J., Jiang, P.X., Jones, T., Kawai, J., Kamiya, A., Meyers, C., Nakajima, M., Narusaka, M., Seki, M., Sakurai, T., Satou, M., Tamse, R., Vaysberg, M., Wallender, E.K., Wong, C., Yamamura, Y., Yuan, S., Shinozaki, K., Davis, R.W., Theologis, A. and Ecker, J.R.:
" Empirical analysis of transcriptional activity in the Arabidopsis genome"
Science, 302, 842-846 (2003) - Kurihara, Y., Matsui, A., Hanada, K., Kawashima, M., Ishida, J., Morosawa, T., Tanaka, M., Kaminuma, E., Mochizuki, Y., Matsushima, A., Toyoda, T., Shinozaki, K. and Seki, M.:
" Genome-wide suppression of aberrant mRNA-like noncoding RNAs by NMD in Arabidopsis"
Proc. Natl. Acad. Sci. USA 106:2453-2458 (2009) - Matsui, A., Ishida, J., Morosawa, T., Mochizuki, Y., Kaminuma, E., Endo, T.A., Okamoto, M., Nambara, E., Nakajima, M., Kawashima, M., Satou, M., Kim, J.M., Kobayashi, N., Toyoda, T., Shinozaki, K. and Seki, M.:
" Arabidopsis Transcriptome Analysis under Drought, Cold, High-Salinity and ABA Treatment Conditions using a Tiling Array."
Plant Cell Physiol. 49: 1135-1149 (2008) (Rapid Report) - Kim, J.M., Kim-To, T., Ishida, J., Morosawa, T., Kawashima, M., Matsui, A., Toyoda, T., Kimura, H., Shinozaki, K. and Seki, M.:
" Alterations of lysine modifications on histone H3 N-tail under drought stress conditions in Arabidopsis thaliana."
Plant Cell Physiol. 49:1580-1588 (2008) - To, T.K., Nakaminami, K., Kim, J.M., Morosawa, T., Ishida, J., Tanaka, M., Yokoyama, S., Shinozaki, K. and Seki, M.:
" Arabidopsis HDA6 is required for freezing tolerance."
Biochem. Biophys. Res. Commun. 406:414-419. (2011) - To, T.K., Kim, J.M., Matsui, A., Kurihara, Y., Morosawa, T., Ishida, J., Tanaka, M., Endo, T., Kakutani, T., Toyoda, T., Kimura, H., Yokoyama, S., Shinozaki, K. and Seki, M.:
" Arabidopsis HDA6 Regulates Locus-Directed Heterochromatin Silencing in Cooperation with MET1."
PLoS Genet. 7:e1002055. (2011) - Utsumi. Y., Sakurai, T., Umemura, Y., Ayling, S., Ishitani, M., Narangajavana, J., Sojikul, P., Triwitayakorn, K., Matsui, M., Manabe, R., Shinozaki, K. and Seki, M.:
" RIKEN Cassava Initiative: Establishment of a cassava functional genomics platform."
Tropical Plant Biol. (in press). (2012)
Principal Investigator
- Motoaki SEKI
- Team Leader
Members
- Jong Myong KIM
- Research Scientist
- Kentaro NAKAMINAMI
- Research Scientist
- Akihiro MATSUI
- Postdoctoral Researcher
- Yoshinori UTSUMI
- Postdoctoral Researcher
- Cam Chau Thi Nguyen
- Student Trainee
- Junko ISHIDA
- Technical Staff
- Taeko MOROSAWA
- Technical Staff
- Sachiko OOYAMA
- Technical Staff
- Seiko NOMURA
- Technical Staff
- Maho TANAKA
- Technical Staff