Laboratory for Cognitive Brain Mapping
Laboratory Head
Keiji TANAKA (Ph.D.)
To reveal mechanisms of higher brain functions such as recognition and decision making, we are conducting experiments with non-human primates and functional MRI with a 4T system on normal human subjects. In the research with non-human primates, the animals are trained with various behavioral paradigms, and effects of functional blocage of particular brain sites or connections are examined and single-cell recordings are conducted during the task performance. We are focusing on the mechanisms of visual object recognition in the inferotemporal cortex and those of goal-directed behavior in the prefrontal cortex. To relate research results in human subjects with those in experimental animals, we are also making efforts to increase the spatial resolution of fMRI with human subjects.
- From the visual object recognition to semantic memory
- Functional differentiation among the prefrontal regions
- Projection-specific functional blockage in macaque monkeys
- fMRI of human cortical functions with columnar spatial resolution
- January 21, 2011
- Researchers uncover neural origins of expert intuition
- July 3, 2009
- Mapping the prefrontal cortex
- October 26, 2007
- Damage to a specific brain area impairs the decision process
- October 15, 2007
- High-resolution brain mapping taken to next level
- April 23, 2007
- Laboratory for Cognitive Brain Mapping of BSI elucidated a neuronal mechanism by which the brain learns correctness/incorrectness.
- Cheng, K., Waggoner, R. A., Tanaka, K.
"Human ocular dominance columns as revealed by high-field functional magnetic resonance imaging."
Neuron, 32, 359-374 (2001). - Matsumoto, K., Suzuki, W., Tanaka, K.
"Neuronal correlates of goal-based motor selection in the prefrontal cortex."
Science, 301, 229-232 (2003). - Gardner, J.L., Sun, P., Waggoner, R.A., Ueno, K., Tanaka, K., Cheng, K.
"Contrast adaptation and representation in human early visual cortex."
Neuron, 47, 1-14 (2005). - Wang, G., Obama, S., Yamashita, W., Sugihara, T., Tanaka, K.
"View-invariant object recognition without experience of object rotations."
Nature Neuroscience, 8, 1568-1575 (2005). - Mansouri, F., Matsumoto, K., Tanaka, K.
"Prefrontal cell activities related to monkeys' success and failure in adapting to rule changes in a Wisconsin Card Sorting Test (WCST) analog."
J. Neuroscience, 26, 2745-2756 (2006). - Matsumoto, M. Matsumoto, K, Abe, H., Tanaka, K.
"Medial Prefrontal Cell Activity Signaling Prediction Errors of Action Values."
Nature Neuroscience, 10, 647-656 (2007) - Matsumoto, M. Matsumoto, K, Abe, H., Tanaka, K.
"Medial Prefrontal Cell Activity Signaling Prediction Errors of Action Values."
Nature Neuroscience, 10, 647-656 (2007) - Mansouri, F.A., Buckley, M.J., Tanaka, K.
"Mnemonic function of lateral prefrontal cortex in conflict-induced behavioral adjustment."
Science 318: 987-990 (2007) - Buckley, M.J., Mansouri, F.A., Hoda, H., Mahboubi, M., Browning, P.G.F., Kwok, S.C., Phillips, A., Tanaka, K.
"Dissociable Components of Rule-Guided Behavior Depend on Distinct Medial and Prefrontal Regions."
Science 325: 52-58 (2009) - Wan, X., Nakatani, H., Ueno, K., Asamizuya, T., Cheng, K., Tanaka, K.
"The neural basis of intuitive best next-move generation in board game experts."
Science 331: 341-346 (2011)
Principal Investigator
- Keiji TANAKA
- Laboratory Head
Members
- Kang CHENG
- Deputy Team Leader
- Takayasu HIGO
- Research Scientist
- Xiaohong WAN
- Research Scientist
- Seiichirou YOKOO
- Research Scientist
- Topi Tapani TANSKANEN
- Research Scientist
- Chien-hui KAO
- Research Scientist
- Farshad Alizadeh MANSOURI
- Research Scientist
- Tsuguo MOGAMI
- Research Scientist
- Pei SUN
- Research Scientist
- R Allen WAGGONER
- Research Specialist
- Masaru KUWABARA
- Research Associate
- Manoj Kumar ERADATH
- International Program Associate
- Florian GERARD-MERCIER
- Intern
- Majid MAHBOUBI
- Technical Staff I
- Yumi NAKAGAWA
- Technical Staff II
- Yasuko TOYOSHIMA
- Assistant
- Mark James BUCKLEY
- Visiting Scientist
- Gang WANG
- Visiting Scientist
- Noritaka ICHINOHE
- Visiting Scientist
- Hiroshi ABE
- Visiting Scientist
- Ayako ISOO
- Visiting Scientist
- Mauro COSTAGLI
- Visiting Scientist
- Sonja GRUEN
- Visiting Scientist
- Alexa RIEHLE
- Visiting Scientist
- Masataka WATANABE
- Visiting Scientist
- Sidney R LEHKY
- Visiting Scientist
- Kenji MATSUMOTO
- Visiting Scientist
- Madoka MATSUMOTO
- Visiting Scientist
- Toshiki TANI
- Visiting Scientist
- Morimitsu FUJII
- Research Collaborative Advisor