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Genome Resource and Analysis Unit
Shigehiro KURAKU
Unit Leader
Shigehiro KURAKU (Ph.D.)
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Research Areas

The Genome Resource and Analysis Unit handles original research projects as well as broad supports of gene sequencing, annotation, expression profiling and distribution of existing clone resources. We will strengthen the focus on comparative genomics, particularly regarding evolution of developmental programs of vertebrates. The Unit also aims to make the best use of rising next-generation sequencing technologies in developmental biology.

Research Subject

  1. Technical support of a wide range of molecular analyses including large-scale gene expression analysis
  2. Development of new solutions for genomics and epigenomics
  3. Technical support of bioinformatic analyses including sequence annotation
  4. Comparative genomic studies of vertebrates

Related links

  1. RIKEN Center for Developmental Biology Website_Laboratories PageNew Window

List of Selected Publications

  1. Kuraku S.:
    "Impact of asymmetric gene repertoire between cyclostomes and gnathostomes."
    Seminars in Cell and Dev Biol. doi:10.1016/j.semcdb.2012.12.009
  2. Oisi Y, Ota KG, Kuraku S, Fujimoto S, and Kuratani S.:
    "Craniofacial development of hagfishes and the evolution of vertebrates."
    Nature. doi:10.1038/nature11794
  3. Matsubara K, Kuraku S, Tarui H, Nishimura O, Nishida C, Agata K, Kumazawa Y, and Matsuda Y.:
    "Intra-genomic GC heterogeneity in sauropsids: evolutionary insights from cDNA mapping and GC3 profiling in snake."
    BMC Genomics. 13: 604 (2012)
  4. Freter S, Muta Y, O'Neill P, Vassilev VS, Kuraku S, Ladher RK.:
    "Pax2 modulates proliferation during specification of the otic and epibranchial placodes."
    Dev Dyn. 241: 1716-1728 (2012)

Members

Principal Investigator

Shigehiro KURAKU
Unit Leader

Members

Mitsutaka KADOTA
Research Scientist
Kazu ITOMI
Technical Staff I
Osamu NISHIMURA
Technical Staff I
Chiharu TANEGASHIMA
Technical Staff II
Kaori TATSUMI
Technical Staff II