Genome Resource and Analysis Unit
Unit Leader
Fumio MATSUZAKI (Ph.D.)
The Genome Resource and Analysis Unit aims to support a wide range of gene analysis research, ranging from DNA sequencing and gene expression analysis to storage and distribution of gene resources. Our facility can perform gene expression analysis and high-throughput gene screening by using the next genelation DNA sequencing system which can analyze ∼500Mb genes/run and DNA microarray systems. Gene resources derived from a variety of species can also be stored and distributed to researchers according to their requests. By building upon existing technology with the challenge of creating new techniques and ideas, as well as providing solid support, we aim to respond flexibly to the needs of each research request.
- Supporting a wide range of gene analysis research including of genome-wide gene expression analysis and genome-wide gene screening
- Creating new techniques and ideas regarding of gene expression analysis
- Supporting of bioinformatics analysis
- Storage and distribution of gene resources derived from a variety of species
- Hayashi, T., Shibata, N., Okumura, R, Kudome, T., Nishimura, O., Tarui, H.,and Agata, K.:
"Single-cell gene profiling of planarian stem cells using fluorescent activated cell sorting and its "index sorting" function for stem cell research."
Dev Growth Differ. 52(1):131-44 (2010) - Maki, N., Martinson, J., Nishimura, O., Tarui, H., Meller, J., Tsonis, PA.,and Agata, K.:
"Expression profiles during dedifferentiation in newt lens regeneration revealed by expressed sequence tags."
Mol Vis. 18;16:72-8 (2010) - Yazawa, S., Umesono, Y., Hayashi, T., Tarui, H.,and Agata, K.:
"Planarian Hedgehog/Patched establishes anterior-posterior polarity by regulating Wnt signaling."
Proc Natl Acad Sci U S A. 106, 22329-34 (2009) - Egger, B., Steinke, D., Tarui, H., De Mulder, K., Arendt, D., Borgonie, G., Funayama, N., Gschwentner, R., Hartenstein, V., Hobmayer, B., Hooge, M., Hrouda, M., Ishida, S., Kobayashi, C., Kuales, G., Nishimura, O., Pfister, D., Rieger, R., Salvenmoser, W., Smith, J., Technau, U., Tyler, S., Agata, K., Salzburger, W.,and Ladurner, P.:
"To be or not to be a flatworm: the acoel controversy."
PLoS One. 4(5):e5502.(2009) - Oral, O., Uchida, I., Eto, K., Nakayama, Y., Nishimura, O., Hirao, Y., Ueda, J., Tarui, H., Agata, K.,and Abé, S.:
"Promotion of spermatogonial proliferation by neuregulin 1 in newt (Cynops pyrrhogaster) testis."
Mech Dev.125(9-10), 906-17(2008) - Ishizuka, H., Maezawa, T., Kawauchi, J., Nodono, H., Hirao, Y., Nishimura, O., Nakagawa, H., Sekii, K., Tasaka, K., Tarui, H., Agata, K., Hoshi, M., Kobayashi, K,, Sakakibara, Y.,and Matsumoto, M.:
"The Dugesia ryukyuensis Database as a Molecular Resource for Studying Switching of the Reproductive System."
Zoolog Sci. 24(1), 31-7 (2007) - Oda, H., Nishimura, O., Hirao, Y., Tarui, H., Agata, K.,and Akiyama-Oda, Y.:
"Progressive activation of Delta-Notch signaling from around the blastopore is required to set up a functional caudal lobe in the spider Achaearanea tepidariorum."
Development. 134(12), 2195-205 (2007) - Sone, M., Hayashi, T., Tarui, H., Agata, K., Takeichi, M.,and Nakagawa, S.:
"The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons."
J Cell Sci. 120(15), 2498-506 (2007) - Matsubara, K., Tarui, H., Toriba, M., Yamada, K., Nishida-Umehara, C., Agata, K.,and Matsuda, Y.:
"Evidence for different origin of sex chromosomes in snakes, birds, and mammals and step-wise differentiation of snake sex chromosomes."
Proc Natl Acad Sci U S A. 103, 18190-5 (2006) - Matsuda, Y., Nishida-Umehara, C., Tarui, H., Kuroiwa, A., Yamada, K., Isobe, T., Ando, J., Fujiwara, A., Hirao, Y., Nishimura, O., Ishijima, J., Hayashi, A., Saito, T., Murakami, T., Murakami, Y., Kuratani, S.,and Agata, K.:
"Highly conserved linkage homology between birds and turtles: bird and turtle chromosomes are precise counterparts of each other."
Chromosome Res. 13(6), 601-15 (2005)