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Animal Resource Unit
Kazuki NAKAO
Unit Leader
Kazuki NAKAO
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Research Areas

Our laboratory provides support services for the care of mice and rats in SPF conditions and the receipt of mutant mice from institutes in Japan and overseas, as well as reproductive services including cleaning and colony establishment through IVF, and lineage preservation by vitrification cryopreservation. We also provide pregnant mice, embryos, and surrogates to support animal research in the CDB, and develop tools and techniques for use in rodent reproductive biotechnology.

Research Subject

  1. Cryopreservation
  2. Development of mouse reproduction technology

Related links

  1. RIKEN Center for Developmental Biology Website_Laboratories PageNew Window

List of Selected Publications

  1. Nakao, K. and Inoue, K.:
    "Cryopreservation for Broader Production of Transgenic Mice by DNA Injection into Zygotes."
    Exp. Anim. 59(2), 225-229(2010).
  2. Kamiya D, Banno S, Sasai N, Ohgushi M, Inomata H, Watanabe K, Kawada M, Yakura R, Kiyonari H, Nakao K, Jakt LM, Nishikawa S, Sasai Y.:
    "Intrinsic transition of embryonic stem-cell differentiation into neural progenitors"
    Nature.24:503-509(2011)
  3. Abe T, Kiyonari H, Shioi G, Inoue K, Nakao K, Aizawa S, Fujimori T.:
    "Establishment of conditional reporter mouse lines at ROSA26locus for live cell imaging."
    Genesis. 49:579-590, (2011)
  4. Shioi G, Kiyonari H, Abe T, Nakao K, Fujimori T, Jang CW, Huang CC, Akiyama H, Behringer RR, Aizawa S.:
    "A mouse reporter line to conditionally mark nuclei and cell membranes for in vivo live-imaging."
    Genesis. 49:570-578, (2011)
  5. Doi M, Ishida A, Miyake A, Sato M, Komatsu R, Yamazaki F, Kimura I, Tsuchiya S, Kori H, Seo K, Yamaguchi Y, Matsuo M, Fustin JM, Tanaka R, Santo Y, Yamada H, Takahashi Y, Araki M, Nakao K, Aizawa S, Kobayashi M, Obrietan K, Tsujimoto G, Okamura H.:
    "Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus."
    Nature Communications, 327: 1316-1324, (2011)

Members

Principal Investigator

Kazuki NAKAO
Unit Leader

Members

Hiroshi KIYONARI
Research Specialist
Mayo SHIGETA
Technical Staff I
Kenichi INOUE
Technical Staff II
Norie TANAKA
Technical Staff II
Sachi YAKAWA
Technical Staff II
Aki SHIRAISHI
Technical Staff II
Tomoko TOKUNAGA
Technical Staff II
Takuya KAWADA
Technical Staff II
Yuki KANEKO
Technical Staff II
Miho SATO
Technical Staff II
Masako NODA
Technical Staff II