Laboratories
"What Make Cells" Research Team
Research Areas
We study the molecular mechanisms that govern the organization and maintenance of cells through the exchange and transport of molecules and information among intracellular compartments. We develop tools and techniques that enable us to visualize lipids and proteins. We employ this and other techniques to understand various cellular events including signal transduction, membrane traffic, cell growth and differentiation.
 

Reizo KATO
Team Head
Toshihide KOBAYASHI (D.Pharm.)
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Research Subject
(1) Development of techniques to observe intracellular molecules
(2) Dynamics of intracellular molecules and compartments
(3) Communication between intracellular organelles
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List of Selected Publications
(1) Takahashi, M., Murate, M., Fukuda, M., Sato, S.B., Ohta, A., and Kobayashi, T.:
鼎holesterol controls lipid endocytosis through Rab11.
Mol. Biol. Cell 18, 2667-2677 (2007).
(2) Iwamoto, K., Hayakawa, T., Murate, M., Makino, A., Ito, K., Fujisawa, T., and Kobayashi, T.:
鼎urvature-dependent recognition of ethanolamine phospholipids by duramycin and cinnamycin.
Biophys. J. 93, 1608-1619 (2007).
(3) Morimatsu, M., Takagi, H., Ota, K.G., Iwamoto, R., Yanagida, T., and Sako, Y.:
溺ultiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis.
Proc. Natl. Acad. Sci. USA 104, 18013-18018 (2007).
(4) Yasuda, G., Nishi, R., Watanabe, E., Mori, T., Iwai, S., Orioli, D., Stefanini, M., Hanaoka, F., and Sugasawa, K.:
的n vivo destabilization and functional defects of the xeroderma pigmentosum C protein caused by a pathogenic missense mutation.
Mol. Cell. Biol. 27, 6606-6614 (2007).
(5) Matsuura-Tokita, K., Takeuchi, M., Ichihara, A., Mikuriya, K., and Nakano, A.:
鏑ive imaging of yeast Golgi cisternal maturation.
Nature 441, 1007-1010 (2006).