Imaging Lipid Research Team
Research Areas
Research group for lipid dynamics will unravel new functions of lipids via "imaging" cellular lipids. Research team for imaging lipids will screen new proteins and small molecules that recognize specific lipid or lipid assemblies. This team will also chemically synthesize probes that sensitize the physical and chemical properties as well as dynamics of lipid membranes. The development of optical and electron microscopy and other techniques to visualize lipids is also an important task of this team.
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Research Subject
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List of Selected Publications
| (1) | Tokunaga, M., Imamoto, N., and Sakata-Sogawa, K.: "Highly inclined thin illumination enables clear single-molecule imaging in cells." Nat Methods. 5, 159-61 (2008). |
| (2) | Takahashi, M., Murate, M., Fukuda, M., Sato, SB., Ohta, A., and Kobayashi, T.: "Cholesterol controls lipid endocytosis through Rab11." Mol. Biol. Cell 18, 2667-2677 (2007). |
| (3) | Hayakawa, T., Makino, A., Murate, M., Sugimoto, I., Hashimoto, Y., Takahashi, H., Ito, K., Fujisawa, T., Matsuo, H., and Kobayashi, T.: "pH-dependent formation of membranous cytoplasmic body-like structure of ganglioside GM1/bis(monoacylglycero)phosphate mixed membranes." Biophys. J. 92, L13-16 (2007). |
| (4) | Iwamoto, K., Hayakawa, T., Murate, M., Makino, A., Ito, K., Fujisawa, T., and Kobayashi, T.: "Curvature-dependent recognition of ethanolamine phospholipids by duramycin and cinnamycin." Biophys. J. 93, 1608-1619 (2007) |
| (5) | Morimatsu, M., Takagi, H., Ota, KG., Iwamoto, R., Yanagida, T., and Sako, Y.: "Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis." Proc Natl Acad Sci U S A. 104, 18013-8 (2007). |