Lipid Functions Research Team
Research Areas
Research team for lipid function studies the new function of lipids by directly visualizing distribution and dynamics of lipids and lipid domains using lipid probes developed by the Research team for imaging lipids. The outcome of the study will be transferred to the Research team for molecular dynamics of lipids for simulation and the theoretical extrapolation of the results using model membranes. The targets of Research team for lipid function are: lipid domains, lipid asymmetry and lipid droplets.
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Research Subject
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List of Selected Publications
| (1) | Baba, A., Akagi, K., Takayanagi, M., Flanagan, JG., Kobayashi, T., and Hattori, M.: "Fyn tyrosine kinase regulates the surface expression of GPI-linked ephrin via the modulation of sphingomyelin metabolism." J. Biol. Chem. 284, 9206-9214 (2009). |
| (2) | Kinoshita, MO., Furuya, S., Ito, S., Shinoda, Y., Yamazaki, Y., Greimel, P., Ito, Y., Hashikawa, T., Machida, T., Nagatsuka, Y., and Hirabayashi, Y.: "Lipid rafts enriched in phosphatidylglucoside direct astroglial differentiation by regulating tyrosine kinase activity of epidermal growth factor receptors." Biochem J. 419, 565-75 (2009). |
| (3) | Kohyama-Koganeya, A., Kim, YJ., Miura, M., and Hirabayashi, Y.: "A Drosophila orphan G protein-coupled receptor BOSS functions as a glucose-responding receptor: loss of boss causes abnormal energy metabolism." Proc. Natl. Acad. Sci. U S A. 105, 15328-33 (2008). |
| (4) | Hirabayashi, Y. and Furuya, S.: "Roles of l-serine and sphingolipid synthesis in brain development and neuronal survival." Prog. Lipid Res. 47, 188-203 (2008) Review. |
| (5) | Nagatsuka, Y. and Hirabayashi, Y.: "Phosphatidylglucoside: a new marker for lipid rafts." Biochim. Biophys. Acta. 1780, 405-9 (2008) Review. |