RIKEN-USM Joint Research Team
Team Head
Hiroyuki OSADA (D.Agr.)
RIKEN-USM Joint Research Team aims to isolate novel biological active compounds from tropical plants found in Southeast Asia, particularly in Malaysia. To achieve this purpose, we collaborate in construction of chemical library, validation of biological activities, and determination of target molecules with Universiti Sains Malaysia (USM). . As a result from the utilization of chemical library, the drugs for tropical diseases in Southeast Asia will be developed.
- Construction of chemical library from natural resources in Penang.
- Screening for chemical compounds which inhibit proliferation of malaria parasite
- Ong, EB., Watanabe, N., Saito, A., Futamura, Y., Abd El Galil, K.H., Koito, A., Najimudin, N., Osada, H.:
Vipirinin, a coumarin-based HIV-1 VPR inhibitor, interacts with a hydrophobic region of VPR.
J Biol. Chem. 286, 14049-14056 (2011).
Principal Investigator
- Hiroyuki OSADA
- Team Head
Staff Scientist
- Nobumoto WATANABE
- Tamio SAITO
- Toshihiko NOGAWA
- ASI Technical Scientist
Postdoctoral Fellow
- Hiroki HAYASE
- Postdoctoral Researcher