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Chemical Bank Unit for Drug Discovery Platform
Tamio SAITO
Unit Leader
Tamio SAITO (D. Agr.)
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Research Areas

Chemical Bank Unit for Drug Discovery Platform prepares chemical library for drug development, and provides them to the researchers in drug-discovery screening. We store the compounds, which are synthesized or purchased during exploration and optimization of drug seeds, and redistributes them for the purposes of validation of biological activity, toxicity or safety. We also develop cheminformatics modules quickly to select the compounds with chemical structure similar to hits, and to enhance of efficiency of compound provision.

Research Subject

  1. Storage of chemical libraries
  2. Distribution of chemical libraries
  3. Development of cheminformatical modules to analyze chemical structures

Related links

  1. RIKEN Advanced Science Institute Website_Laboratories PageNew Window

List of Selected Publications

  1. Saito, T., Lepp, Z., Osada, H.:
    "Chemical screening database."
    THE LUNG perspectives, 17(3), 61-66 (2009)
  2. Osada, H. and Hertwech, C.:
    "Exploring the chemical space of microbial natural products."
    Curr. Opn. Chem. Biol., 13, 133--134 (2009)

Members

Principal Investigator

Tamio SAITO
Unit Leader