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Bio-research Infrastructure Construction Team
Hideo YOKOTA
Team Head
Hideo YOKOTA (D.Eng.)
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Research Areas

Our goal is to develop original RIKEN data processing technology and multidimensional measurement technology in order to contribute to understanding biological phenomena.
We are especially contributing to the fields of mathematical biology, bio-medical simulations as well as medical diagnostic and treatment technology by researching and developing new data and image processing technologies and establishing new tools for quantification of biological phenomena, intended for researchers both inside and outside RIKEN.

Research Subject

  1. Development of bio-research infrastructure systems.
  2. Construction of live cell model describing phenomenon of living cell.
  3. Construction of instrumentation system for bio-research data creation.

Related links

  1. RIKEN Advanced Science Institute Website_Laboratories PageNew Window
  2. Individual Website Laboratory PageNew Window

Press release

March 3, 2011
New system developed for three dimensional analysis of material element distribution
August 16
Formation of nuclear membrane cavity complex directed by cell cycle engine
June 3, 2010
3D microscopy with micro-meter resolution reveals internal structures of industrial materials, parts, and products
October 06, 2009
Ultra fine grain binderless cBN (cubic Boron-Nitrogen) cutting tool developed for steel-based mirrored surface manufacturing
August 17, 2009
Three-dimensional analysis technology for studying formation of fine inclusions in steel materials
August 12, 2008
Development of a high-resolution in vivo-CT system for the measurement of small animals using high luminosity synchrotron radiation as a light source

RIKEN RESEARCH

October 15, 2010
Improving pore 'vision
The formation of nuclear pores in dividing human cells is being illuminated by new visualization techniques New Window
November 07, 2008
Catching the heart and lungs in action
A newly developed micro-CT system produces images sharp enough to detect the motion of arteries and small airways in rats and mice New Window
September 21, 2007
Computational living cell modeling New Window

List of Selected Publications

  1. Kazuhiro Fujisaki, Hideo Yokota , Naomichi Furushiro ,Shintaro Komatani, Sumito Ohzawa , Yoshimichi Sato ,Daisuke Matsunaga ,Ryutaro Himeno , Toshiro Higuchi, Akitake Makinouchi.:
    "Three-Dimensional Microscopic Elemental Analysis Using an Automated High-Precision Serial Sectioning System"
    Microscopy and Microanalysis, volume 17, issue 02, pp. 246-251.2011
  2. Takashi Ijiri and Hideo Yokota.:
    "Contour-based Interface for Refining Volume Segmentation"
    Computer Graphics Forum, 29(2011), 7, 2153-2160.
  3. Maeshima K, Iino H, Hihara S, Funakoshi T, Watanabe A, Nishimura M, Nakatomi R, Yahata K, Imamoto F, Hashikawa T, Yokota H, and Imamoto N.:
    "Nuclear Pore Formation, but Not Nuclear Growth, is Governed by Cyclin-dependent Kinases (Cdks) During Interphase in Human Dividing Cells"
    Nature Structure & Molecular Biology,17,pp.1065-1071(2010)
  4. S. Yoshizawa, A. Belyaev, and H. Yokota.:
    "Fast Gauss Bilateral Filtering"
    Computer Graphics Forum The International Journal of Eurographics Association, Vol.29(1), pp. 60-74, 2010.
  5. K. Fujisaki, H.Yokota, H. Nakatsuchi, Y. Yamagata, T. Nishikawa, T. Udagawa and A. Makinouchi.:
    "Observation of three-dimensional internal structure of steel materials by means of serial sectioning with ultrasonic elliptical vibration cutting"
    Journal of Microscopy,vol.237, 1, pp.89-95, (2010)
  6. Kazuhiro Fujisaki, Hideo Yokota, Naomichi Furushiro, Yutaka Yamagata, Takashi Taniguchi, Ryutaro Himeno, Akitake Makinouchi, Toshiro Higuchi.:
    "Development of ultra-fine-grain binderless cBN tool for precision cutting of ferrous materials"
    Journal of Materials Processing Technology, vol.209, 15-16, pp.5646-5652, (2009)
  7. Satoko Takemoto, Hideo Yokota, Taketoshi Mishima and Ryutaro Himeno.:
    "Segmentation of Anatomical Structure by Using a Local Classifier Derived from Neighborhood Information"
    Human-Computer Systems Interaction, Series: Advances in Intelligent and Soft Computing, Vol. 60, pp.171-180, Springer-Verlag, Berlin Heidelberg, 2009.
  8. Shin Yoshizawa, Satoko Takemoto, Miwa Takahashi, Makoto Muroi, Sayaka Kazami, Hiromi Miyoshi, and Hideo Yokota.:
    "Intracellular Volume Registration"
    International Conference on Intelligent Systems Design and Applications, pp. 1407-1412, November 30-December 2, 2009, Pisa, Italy.
  9. Satoko Takemoto and Hideo Yokota.:
    "Algorithm Selection for Intracellular Image Segmentation based on Region Similarity"
    International Conference on Intelligent Systems Design and Applications, pp. 1413-1418, November 30-December 2, 2009, Pisa, Italy.
  10. T. Ijiri, K. Takayama, H. Yokota, and T. Igarashi.:
    "ProcDef: Local-to-global Deformation for Skeleton-free Character Animation"
    Computer Graphics Forum: The International Journal of Eurographics Association (Proc. of Pacific Graphics), Vol.28(7), pp. 1821-1828, 2009.

Members

Principal Investigator

Hideo YOKOTA
Team Head

Staff Scientist

Shin YOSHIZAWA
ASI Research Scientist

Postdoctoral Fellow

Takashi IJIRI
Special Postdoctoral Researcher
Satoko KANAUCHI-TAKEMOTO
Postdoctoral Researcher

Technical Assistant

Sakiko NAKAMURA
Technical Staff I
Yuki TSUJIMURA
Technical Staff I
Masaomi NISHIMURA
Technical Staff I
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