Novel PET Diagnostics Laboratory

Positron emission tomography (PET) is a non-invasive medical imaging technique used in the diagnosis and treatment of diseases (eg. tumor diagnosis in oncology), using an extremely small amount of positron-emitting radioactive compound.
At present, 2-[18F]Fluoro-2-deoxy-D-glucose (FDG) is widely utilized in PET clinically, for tumor diagnosis. However, FDG has several serious limitations. For example, the high physiological uptake of FDG in normal tissues, such as the brain, can complicate the diagnostic evaluation of tumors in these locations. Furthermore, numerous inflammatory conditions can lead to increased local FDG uptake which can result in false positive results.
Presently, we are developing novel positron-emitting radioactive compounds to be used diagnostically in PET to resolve the above issues.

Research Subjects

• Development of novel PET diagnostic agents