Benno Laboratory

By measuring/evaluating individual physiological/metabolic function, mainly in human large intestine, with certain intervals in details, we establish a technological system that can categorize the lifestyle related diseases. We also establish the sysytematic isolation for unclutured gut bacteria.

Research Subjects

• Research and development of the test meal that makes categorization/ evaluation of intended illness easier
• Feeding test on the test meal and precise analysis on feces
• Systematic isolation of unclutured gut bacteria

Publications

1. Sato H., Teramoto K, Ishii Y., Watanabe K., and Benno Y.:
   "Ribosomal protein profiling by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for phylogenety-based subspecies resolution of Bifidobacterium longum."
   Syst. Appl. Microbiol., 34: 76-80 (2011)
2. Kurihara S., Suzuki H., Oshida M., and Benno Y.:
   "A novel putrescine importer required for type 1polli-driven suface surface motility induced by extracellular putrescine in Escherichia coli K-12."
   J. Biol. Chem. 286: 10185-10192 (2011)
3. Matsumoto M, Kurihara S., Kibe R, Ashida H., and Benno Y.:
   "Longevity in mice is promoted by probiotic-induced suppression of colonic senescence dependent on upergulation of gut bacterial polyamine production."
   PloS One 6: e23652 (2011)
4. Satoh K., Nishiyama Y., Yamazaki T., Sugita T., Tsukii U., Takatori K., Benno Y., and Makimura K.:
   "Microbe-1: Fungal biota analyses of Japanese experimental module KIBO, international space station which passed for about 460 days"
   Microbiol. Immunol. 55: 823-829 (2011)
5. Kitahara M., Sakamoto M., Tsuchida S., Kawasumi K., Amao H., Benno Y., and Ohkuma M.:
   "Bacteroides stercorirosoris sp. nov. and Bacteroides faecichinchillae sp. nov., isolated from chinchilla (Chincilla lanigera) faeces"
   Int J Syst Evol Microbiol. 61: 877-881 (2011)
6. Matsumoto M., Kibe R., Ohga T., Aiba Y., Kurihara S., Sawaki E., Koga Y., and Benno Y.:
   "Impact of intestinal microbiota on intestinal luminal metabolome."
   Sci. Report , 2: 233; DOI:10.1038/srep00233 (2012)
7. Matsumoto M, Kurihara S., Kibe R, Ashida H., and Benno Y.:
   "Longevity in mice is promoted by probiotic-induced suppression of colonic senescence dependent on upergulation of gut bacterial polyamine production."
   PloS One 6: e23652 (2011)
8. Odamaki T, Sugahara H, Yonezawa S, Yaeshima T, Iwatsuki K, Tanabe S,Tominaga T, Togashi H, Benno Y, Xiao J-Z.:
   "Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota."
   Anaerobe. 18 :14-18 (2012)
9. Jin J.S., Touyama M., Hisada T., and Benno Y.:
   "Effect of green tea on human faecal microbiota with a special reference to Bifidobacterium species"
   Microbiol. Immunol., 56: 729-739 (2012)
10. Jin J.S., Touyama M., Kibe R., Benno Y., Kobayashi T, Tanaka Y., Yamamura H., Shimakawa M., Maruo T., Toda T., Matsumoto T., Chounan O., Seo G., Matsuda I., Tagami H., and Benno Y.:
    "Analysis of the human intestinal microbiota from 92 volunteers after ingestion of identical meals"
    Beneficial Microb.30: 27-33 (2012)