Image Processing Research Team

Our goal is to develop original RIKEN data processing technology and multidimensional measurement technology in order to contribute to understanding biological phenomena. We are especially contributing to the fields of mathematical biology, bio-medical simulations as well as medical diagnostic and treatment technology by researching and developing new data and image processing technologies and establishing new tools for quantification of biological phenomena, intended for researchers both inside and outside RIKEN.

Research Fields

Engineering / Biology & Biochemistry / Clinical Medicine / Computer Science / Mathematics

Research Subjects

• Development of bio-research infrastructure systems.
• Construction of live cell model describing phenomenon of living cell.
• Construction of instrumentation system for bio-research data creation.

Publications

1. Yuko Okamura-Oho*, Kazuro Shimokawa, Satoko Takemoto, Asami Hirakiyama, Sakiko Nakamura, Yuki Tsujimura, Masaomi Nishimura, Takeya Kasukawa, Koh-hei Masumoto, Itoshi Nikaido, Yasufumi Shigeyoshi, Hiroki R. Ueda, Gang Song, James Gee, Ryutaro Himeno, Hideo Yokota
   Transcriptome tomography for brain analysis in the web-accessible anatomical space
   PLOS ONE Doi: 10.1371/journal.pone.0045373 (2012)
2. S. Hihara, C.-G. Pack, K. Kaizu, T. Tani, T. Hanafusa, T. Nozaki, S. Takemoto, T. Yoshimi, H. Yokota, N. Imamoto, Y. Sako, M. Kinjo, K. Takahashi, T. Nagai, and K. Maeshima
   Local Nucleosome Dynamics Facilitate Chromatin Accessibility in Living Mammalian Cells
   Cell Reports, Vol. 2(6), pp. 1645-1656, 2012.
3. Katsuya Kominami, Takeharu Nagai, Tatsuya Sawasaki, Yuki Tsujimura, Kenta Yashima, Yasuhiro Sunaga, Masateru Tsuchimochi, Jun Nishimura, Kumiko Chiba, Jun Nakabayashi, Koji Koyamada, Yaeta Endo, Hideo Yokota, Atsushi Miyawaki, Noboru Manabe, Kazuhiro Sakamaki
   In Vivo Imaging of Hierarchical Spatiotemporal Activation of Caspase-8 during Apoptosis
   PLoS ONE 7(11): e50218. doi:10.1371/journal.pone.0050218 (2012)
4. Ijiri T, Ashihara T, Umetani N, Igarashi T, Haraguchi R, Yokota H, Nakazawa K
   A Kinematic Approach for Efficient and Robust Simulation of the Cardiac Beating Motion
   PLoS ONE 7(5): e36706. doi:10.1371/journal.pone.0036706
5. Kazuhiro Fujisaki, Hideo Yokota , Naomichi Furushiro ,Shintaro Komatani, Sumito Ohzawa , Yoshimichi Sato ,Daisuke Matsunaga ,Ryutaro Himeno , Toshiro Higuchi, Akitake Makinouchi,
   "Three-Dimensional Microscopic Elemental Analysis Using an Automated High-Precision Serial Sectioning System"
   Microscopy and Microanalysis, volume 17, issue 02, pp. 246-251.2011
6. Takashi Ijiri and Hideo Yokota:
   "Contour-based Interface for Refining Volume Segmentation"
   Computer Graphics Forum, 29(2011), 7, 2153-2160.
7. Maeshima K, Iino H, Hihara S, Funakoshi T, Watanabe A, Nishimura M, Nakatomi R, Yahata K, Imamoto F, Hashikawa T, Yokota H, and Imamoto N,
   "Nuclear Pore Formation, but Not Nuclear Growth, is Governed by Cyclin-dependent Kinases (Cdks) During Interphase in Human Dividing Cells"
   Nature Structure & Molecular Biology,17,pp.1065-1071(2010)
8. S. Yoshizawa, A. Belyaev, and H. Yokota,
   "Fast Gauss Bilateral Filtering"
   Computer Graphics Forum The International Journal of Eurographics Association, Vol.29(1), pp. 60-74, 2010.
9. K. Fujisaki, H.Yokota, H. Nakatsuchi, Y. Yamagata, T. Nishikawa, T. Udagawa and A. Makinouchi,
   "Observation of three-dimensional internal structure of steel materials by means of serial sectioning with ultrasonic elliptical vibration cutting"
   Journal of Microscopy,vol.237, 1, pp.89-95, (2010)
10. T. Ijiri, K. Takayama, H. Yokota, and T. Igarashi,
    "ProcDef: Local-to-global Deformation for Skeleton-free Character Animation"
    Computer Graphics Forum: The International Journal of Eurographics Association (Proc. of Pacific Graphics), Vol.28(7), pp. 1821-1828, 2009.