RIKEN Quantitative Biology Center (QBiC)

Director:: Toshio Yanagida; (Ph.D.)

Cells are dynamic living systems that arise from a large number of molecules interacting with one another. The RIKEN Quantitative Biology Center seeks to understand how these molecular interactions lead to functional cells. Combining techniques that can measure molecular dynamics, model cellular environments, and simulate molecular and genetic networks, the center aims to understand the robustness, adaptability, and autonomy of a cell that leads to these dynamics, with the ultimate goal of achieving “whole cell modeling”. These efforts are expected to predict and control a cell’s behavior, which will have large implications in wide fields like regenerative medicine and nanotechnology.

Organization

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Cell Dynamics Research Core

Toshio Yanagida(Ph.D.)
- Laboratory for Cell Dynamics Observation
  
  Toshio Yanagida(Ph.D.)
  - Laboratory for Single Cell Gene Dynamics
    
    Yuichi Taniguchi(Ph.D.)
  - Laboratory for Cell Field Structure
    
    Atsuko Iwane
- Laboratory for Cell Signaling Dynamics
  
  Masahiro Ueda(Ph.D.)
- Laboratory for Comprehensive Bioimaging
  
  Tomonobu Watanabe(Ph.D.)
- Laboratory for Nano-Bio Probes
  
  Takashi Jin(D. Sci.)
- Laboratory for Single Cell Mass Spectrometry
  
  Tsutomu Masujima(Ph.D.)
- Laboratory for Developmental Dynamics
  
  Shuichi Onami(D.V.M., Ph.D.)
- Laboratory for Cell Polarity Regulation
  
  Yasushi Okada(M.D., Ph.D.)
- Laboratory for Biomolecular Structure and Dynamics
  
  Takanori Kigawa(Ph.D.)

Computational Biology Research Core

Makoto Taiji(D. Sci.)
- Laboratory for Computational Molecular Design
  
  Makoto Taiji(D. Sci.)
  - Drug Discovery Molecular Simulation Platform Unit
    
    Makoto Taiji(D. Sci.)
- Laboratory for Biomolecular Function Simulation
  
  Yuji Sugita(D. Sci.)
- Laboratory for Biochemical Simulation
  
  Koichi Takahashi(Ph.D.)
- Laboratory for Multiscale Biosystem Dynamics
  
  Chikara Furusawa(Ph.D.)

Cell Design Research Core

Hiroki Ueda(M.D., Ph.D.)
- Laboratory for Synthetic Biology
  
  Hiroki Ueda(M.D., Ph.D.)
  - Laboratory for Cell-Free Protein Synthesis
    
    Yoshihiro Shimizu(Ph.D.)
  - Laboratory for Integrated Biodevice
    
    Yo Tanaka(Ph.D. (Eng.))

Laboratory for Cardiovascular Molecular Dynamics

Atsuo Kawahara(Ph.D.)

Office for Multicellular Dynamics Research Collaboration

Yoshiki Sasai(M.D., Ph.D.)

Office for Supramolecular System Dynamics Research Collaboration

Keiichi Nanba(D.Eng.)

Office for Cellular Structural Biology Research Collaboration

Takanori Kigawa(Ph.D.)

Frey Initiative Research Unit

Urs Frey(D. Sci.)

RIKEN Quantitative Biology Center (QBiC)

Organization

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