We are developing an NMR spectrometer with a magnetic field intensity stronger than those ever achieved, along with super-high sensitivity NMR probes and novel NMR measurement methods, in order to delineate conformation change of proteins in solution with ultra-high resolution. Additionally, we act as a core institute for an NMR platform between large NMR facilities in Japan.

Research Fields

Physics / Engineering / Chemistry / Materials Sciences / Biology & Biochemistry / Molecular Biology & Genetics / Pharmacology & Toxicology / Agricultural Sciences / Environment & Ecology

Research Subjects

• Development of NMR spectrometers using high-temperature superconducting magnets operated beyond 1GHz
• Development of ultra-sensitivity NMR probe using high temperature superconducting RF coil
• Basic investigation on the next generation REBCO high-temperature superconducting magnet technology

Publications

1. Takahashi, M., Ebisawa, Y., Tennmei, K., Yanagisawa, Y., Hosono, M., Takasugi, K., Hase, T., Miyazaki, T., Fujito, T., Nakagome, H., Kiyoshi, T., Yamazaki, T., and Maeda, H.,
   “Towards a beyond 1GHz solid-state nuclear magnetic resonance: external lock operation in an eternal current mode for a 500MHz nuclear magnetic resonance”,
   Rev. Sci. Instrum. 83, 105110 (2012).
2. Yanagisawa. Y, Sato, K., Piao, R., Nakagome, H., Takematsu, T., Takao, T., Kamibayashi, H., Takahashi, M., and Maeda, H.,
   “Removal of degradation of the performance of the performance of an epoxy impregnated YBCO-coated conductor double pancake coil by using a polyimide-electrodeposited YBCO-coated conductor”,
   Physica C 476, 19-22(2012).
3. Yanagisawa, Y., Okuyama, E., Nakagome, H., Takemastu, T., Takao, T., Hamada, M., Matsumoto, S., Kiyoshi, T., Takizawa, A., and Maeda, H.,
   The mechanism of thermal runaway due to continuous local disturbances in the YBCO-coated conductor coil winding,
   Supercond. Sci. Technol. 25, 075014 (2012).
4. Y. Yanagisawa, Y. Kominato, S. Matsumoto, K. Zaitsu, T. Hase, T. Miyazaki, M. Hamada, M. Hosono, and H. Maeda,
   Magnitude of the screening field for YBCO coils,
   IEEE Trans Appl. Supercond., 21, 1640-1643 (2011).
5. Takematsu, T., Hu, R., Takao, T., Yanagisawa, Y., Nakagome. Uglietti, D., Kiyoshi, T., Takahashi, M, and Maeda, H.,
   “Degradation of the performance of a YBCO-coated conductor double pancake coil due to epoxy impregnation”,
   Physica C 470, 674(2010)
6. Hobo, F., Takahashi, M., Saito, Y., Sato, N., Takao, T., Koshiba, S., and Maeda, H.
   “33S NMR spectroscopy of biological samples obtained with a laboratory model 33S cryogenic probe”,
   Rev. Sci. Instrum. 81, 054302 (2010).
7. Yanagisawa, Y., Nakagome, H., Tennmei, K., Hamada, M., Yoshikawa, M., Otsuka, A., Hosono, M., Kiyoshi, T., Takahashi, M., Yamazaki, T., and Maeda, H.,
   “Operation of a 500 MHz high temperature superconducting NMR: Towards an NMR spectrometer operating beyond 1 GH”
   J. Mag. Res. 203, 274-282 (2010).
8. Koyama, Y., Takao, T., Yanagisawa, Y., Nakagome, H., Hamada, M., Kiyoshi, T., Takahashi, M. and Maeda, H.,
   “Towards beyond 1GHz NMR: mechanism of the long term drift of screening current-induced magnetic field in a Bi-2223 coil”,
   Physica C, 469, 694-701 (2009).
9. Kiyoshi, T., Otsuka, A., Choi, S., Matsumoto, S., Zaitsu, S., Hase, T., Hamada, M., Hosono, M., Takahashi, M., Yamazaki, T., and Maeda, H.,
   “NMR Upgrading Project towards 1.05GHz”,
   IEEE Trans. Appl. Superconduct. 18, p860-863(2008).
10. Yoshimoto, F., Takahashi, M., Horiuchi, T., Hobo, F., Inoue, K., Miki, T., Hamada, M., Okamura, T., Yokoyama, S. and Maeda, H.,
    “4 Kelvin cryogenic probe for 500MHz NMR”,
    Adv. Cryogenic Engineerin 51, p704-711 (2006).

Organization